Lookup to what main hubs John Wayne Airport flies.. and then figure out which has the best deals to Germany. Flying to say Denver or Chicago.. and then to SNA may be better for you overall than flying to LAX. SNA is close enough you can take an affordable cab or shuttle and the scale and age of the airport is much more agreeable than LAX.
Thanks as well for the tip! But there are several reasons why LAX makes more sense for me: My local airport is only 20 minute away by underground (station in front of my house, direct train to airport), but does not have any intercontinental flights. So I need to connect in Europe anyway - and I prefer to only have two legs, not three legs on a long flight. Second, I try to avoid having to catch a connecting flight in the US when I first enter the country. You never know how long it takes to get through immigration and I really don't want to stand in a line that beats the standby line for RSR at DL getting in panic of missing my connecting flight and then repeat this for security and then navigate through a huge airport from the international terminal to the one that the domestic flight departs from. And finally, it's just much nicer to be able to get off the long flight and know that that's it and I don't have to get back on a plane again. I hate that coming back as well, but then I am in a bad mood anyway because the vacation is over...