Coronavirus and Walt Disney World general discussion

[MisterPenguin]

Helper immune cells key to helping Pfizer's mRNA COVID-19 vaccine stave off death

As the world grapples with yet another variant of concern in the global COVID-19 pandemic, a new study shows how Pfizer-BioNTech's messenger RNA vaccine helps the immune system remember pathogens a | A type of helper immune cell is key to the Pfizer vaccine's delivery of a long-lasting punch...

www.fiercebiotech.com

Novavax Submits Final Data Packages to U.S. FDA as Prerequisite to Emergency Use Authorization Application Request for COVID-19 Vaccine - Dec 31, 2021

Novavax, Inc. (Nasdaq: NVAX), a biotechnology company dedicated to developing and commercializing next-generation vaccines for serious infectious diseases, today announced that it has completed...

ir.novavax.com

A formal request for EUA should be happening in a month.

 

[sullyinMT]

Unsurprisingly for a Bloomberg article on health issues, the very text of the article that says this...

“When your denominator is very large because many, many people are getting infected, you still wind up having many people going to the hospital who need care,” Justman said. Higher case numbers will also still create disruption in work, travel and schooling​

Contradicts their clickbait byline...

Data suggest hospitalizations are now decoupled from case numbers, and the variant causes less severe disease​

There is zero "decoupling" of cases v. hospitalization. They are very much *coupled*. Hospitalizations are spiking everywhere precisely because of Omicron. The good news is that Omicron leads to hospitalization less often (but not *decoupled*). The bad news is that Omicron is many times more infectious, leading to new record highs in hospitalization... due to that pesky "coupling."

View attachment 612084

Thank you. Where Omicron likely does decouple or not carry hospitalizations with it is in the vaccinated (and apparently boosted).

Why people continue to denounce the role of our incredible vaccine tools is beyond me.

 

[Nubs70]

We are low on inventory and thus are limiting it only to unvaccinated individuals with risk factors and vaxxed people who are immunosuppressed (the poster I was replying to said he was vaxxed.)

Did not the producers stockpile product between surges?

 

[mkt]

If it was so easy a mandate could end this why haven’t any done it yet?

Legally it isn't a problem. But it is political suicide, and there's nothing that the political class wants less than to lose and have to get a real job.

 

[mkt]

Did not the producers stockpile product between surges?

If you look at it globally, there was no "between surges".

It's likely supplies that would have been stockpiled in the US were exported to other countries that were experiencing their own surges at the same time.

 

[Andrew C]

Unsurprisingly for a Bloomberg article on health issues, the very text of the article that says this...

“When your denominator is very large because many, many people are getting infected, you still wind up having many people going to the hospital who need care,” Justman said. Higher case numbers will also still create disruption in work, travel and schooling​

Contradicts their clickbait byline...

Data suggest hospitalizations are now decoupled from case numbers, and the variant causes less severe disease​

There is zero "decoupling" of cases v. hospitalization. They are very much *coupled*. Hospitalizations are spiking everywhere precisely because of Omicron. The good news is that Omicron leads to hospitalization less often (but not *decoupled*). The bad news is that Omicron is many times more infectious, leading to new record highs in hospitalization... due to that pesky "coupling."

View attachment 612084

How much of the hospitalizations at the moment are due to delta? We saw the the other week that the CDC greatly overestimated how many active cases were omicron rather then delta. I imagine that omicron has closed in now, but I also imagine this isn't picked up in hospitalizations yet.

 

[Nubs70]

And your anti vaccine mandate TX governor is now asking for federal assistance to combat covid? I find that back to normal very hard to believe and I have friends who live and work in Houston that would agree.

Anti vax mandate and vax mandate governors have both asked for and received federal assistance.

 

[Chip Chipperson]

Did not the producers stockpile product between surges?

These products have a finite shelf life. I received a shipment of BinaxNOW tests a few weeks ago. The expiration date is October 2022.

 

[Nubs70]

If you look at it globally, there was no "between surges".

It's likely supplies that would have been stockpiled in the US were exported to other countries that were experiencing their own surges at the same time.

We're mcab's actually exported ?

 

[mkt]

We're mcab's actually exported ?

They could well be, and the ones in the US could have been imported. Monoclonal Antibodies are manufactured all over.

 

[Nubs70]

They could well be, and the ones in the US could have been imported. Monoclonal Antibodies are manufactured all over.

The US has not increased domestic production capability in the last year?

 

[Andrew C]

If the goal is to end the pandemic, even a federal vaccine mandate for all won't get you there because there is the rest of the world to consider.
If the goal is the keep as many people out of the hospital as possible, states may want to consider state-wide vaccine mandates, including boosters...and deal with any negative consequences that result (and there will be some for sure).

 

[Chip Chipperson]

The US has not increased domestic production capability in the last year?

There's this weird virus going around that has impacted manufacturers' ability to produce endless quantities of things.

 

[mkt]

The US has not increased domestic production capability in the last year?

The only thing I could find was an article from a year ago stating that Regeneron was certain that they could increase production of them.

 

[carolina_yankee]

25,000+ more new PCR positive in NJ today, plus another 5000+ antigen positives.

Hospitalizations are at 5100. COVID peak (or as far as the graph goes back) was April 28, 2020 at 6200. Eleven days ago on Christmas Eve,, our hospitalizations were 2395. State is building in extra hospital capacity. Problem - no staff. In our previous peak we were staffing with travel teams from other states. Guess what, they are needed back home now.

I don't take the fatalism that everyone is going to get this. I work in an office unmasked (private office), mask when I meet people, mask for services on Sunday except when preaching, and have a husband who is a hospice chaplain and visit facilities. Neither of us has gotten sick (unless we were asymptomatic). We hang out with a close circle of vaccinated friends and order in. We shop, but masked.

Simple precautions for a few weeks can help healthcare workers not want to strangle us if we have to show up, and might mean our elective procedures won't be canceled.

Oh, and if you do want a test, good luck . . .

Dirk

 

[Andrew C]

Death rates are "interesting" so far...

 

[LittleBuford]

I don't take the fatalism that everyone is going to get this.

I don’t think it’s fatalistic to acknowledge that we are all very likely going to contract COVID sooner or later; this is now the medical consensus (if I’m not mistaken). Of course, the doesn’t mean we shouldn’t protect ourselves and society at large by getting vaccinated and taking additional steps (masking, distancing, etc.) to slow the spread.

 

[Vegas Disney Fan]

There are many states that can pass it through their legislature and the governor will/may sign it into law. But there are of course consequences to doing so. And I am not talking just about political ones.

This is the reality, I’d love to see everyone vaccinated, preferably voluntarily, it would save tons of lives and minimize hospitalizations.

I just get annoyed with the argument that it’s one sides fault.

 

[Touchdown]

Did not the producers stockpile product between surges?

That stuff has an expiration date too, you can’t stockpile indefinitely.

 

[The Mom]

Many of you are crossing the line into politics - please stop.