Something to consider, we are flying into Vegas and renting a car, going to see the grand canyon and maybe a Vegas show then make the 4 1/2 hour drive to Anaheim. Turned out flights and rental cars were cheaper in Vegas and we wanted to see the grand canton so it was a better deal than flying into LA/Anaheim.
Something to consider - thanks - I've been looking at the cost of Coaches (they travel between Anaheim, LA, San Diego and Las Vegas). If we used them, then the only thing that we would need to organise is how to get to San Francisco and Yosemite.