I don't see that happening with WoL, but something else could go in there and even have a way to utilize the now empty simulator bays. But it will not ever be able to be the original again. Now for East & West that certainly can be done, not cheaply, but it can be recreated with updated technology.
Yes, it could go in there, but, it will be a slightly different concept if it does. The general health theme will be thrown out and a more technical experience type of study of basic body and mind concepts might be addressed. I'm not sure how they would flesh out the "Inside Out" concept to fill the pavilion.
Does anyone know the reason why Innoventions and EPCOT in general has trouble finding/maintain sponsors? ON the surface, it feels like an ideal partnership for technology companies and corporation to get in on, which was exemplified when EPCOT first opened.