Covid Vaccine Updates and General Discussion About Vaccines

Will you take a Covid vaccine once one is approved and deemed safe and effective by the FDA?

  • Yes, stick me please

  • No, I will wait

  • No, I will never take one


Results are only viewable after voting.

danlb_2000

Premium Member
Sometimes, the virus mutation actually works to our advantage, if it weakens the protein function. In addition to the effective measures taken by public health agencies (including that evil WHO!), it is speculated that SARS-CoV-1 disappeared by basically mutating itself into extinction.

I read a few articles on CoV-1 and haven't seen any mention of mutation. Most say reason for it being contained was that it was mainly transmitted by people who were sick, and those people got very sick, very quickly so could easily be identified and isolated.
 

GoofGoof

Premium Member
Original Poster
New poll out shows 60% of Americans would get a vaccine if it was available today. This is up from 51% in Sept but down from 72% in May. Of the 40% who say they probably (21%) or definitely (18%) wouldn’t get the vaccine 46% say they would consider getting the vaccine after seeing others get it and more information is available. That adds 18% to the original 60% to get to a total of 78% of the population. With a vaccine that’s at least 90% effective that means 70%+ immune which should be good enough to reach herd immunity.

On distribution timing, the 60% ready to go now is just under 200M Americans so likely to take at least 4-6 months to vaccinate. By that time the other 40% will have plenty of data to go on. These numbers are likely to improve over time too as more people start to take the vaccine and there’s a public PR push to ensure people it’s safe and effective.

 

GoofGoof

Premium Member
Original Poster
Interesting read on whether Covid vaccines will be required. Short answer is not by the federal government, but maybe for individual workers or students. As long as the vaccine is under EUA it’s unlikely that any employer or school will mandate getting it. After full FDA approval some employers may require it (especially for healthcare workers or other higher risk jobs) and schools and colleges may require it as well. There’s a lot of precedent for those things. The states technically have the legal authority to mandate vaccinations. Over 100 years ago when smallpox was an issue the Supreme Court upheld the state of Massachusetts’ vaccine law.

 

ToTBellHop

Well-Known Member
Interesting read on whether Covid vaccines will be required. Short answer is not by the federal government, but maybe for individual workers or students. As long as the vaccine is under EUA it’s unlikely that any employer or school will mandate getting it. After full FDA approval some employers may require it (especially for healthcare workers or other higher risk jobs) and schools and colleges may require it as well. There’s a lot of precedent for those things. The states technically have the legal authority to mandate vaccinations. Over 100 years ago when smallpox was an issue the Supreme Court upheld the state of Massachusetts’ vaccine law.

Especially during a health emergency, there is tremendous legal precedent for mandates. Areas in NYC recently required a measles vaccine (or be fined) during an outbreak.
 

GoofGoof

Premium Member
Original Poster
Especially during a health emergency, there is tremendous legal precedent for mandates. Areas in NYC recently required a measles vaccine (or be fined) during an outbreak.
Yes, that was more recent than smallpox too. I think the only difference is the measles vaccine is widely accepted and ofn to be safe for years. I think once a Covid vaccine gets full approval it could very well end up being mandated in certain situations.
 

ToTBellHop

Well-Known Member
Yes, that was more recent than smallpox too. I think the only difference is the measles vaccine is widely accepted and ofn to be safe for years. I think once a Covid vaccine gets full approval it could very well end up being mandated in certain situations.
Exactly. I agree there won’t be mandates under EUA.
 

ToTBellHop

Well-Known Member
I don’t need a mandate. Stick me now :)

I already said this, but I have 2 arms so I’d take em both at the same time if offered :)
Do you need the biology lesson I wrote on Facebook that went low-grade viral (i.e. it spread as quickly as it does when properly wearing a mask)
 

GoofGoof

Premium Member
Original Poster
Do you need the biology lesson I wrote on Facebook that went low-grade viral (i.e. it spread as quickly as it does when properly wearing a mask)
I probably have learned more about vaccines in the last 9 months than I ever wanted to;)

I am joking about getting both vaccines at once, but does anyone know what happens to someone who already had Covid? Can they get the vaccine still? Especially with the suspicion that a number of people had Covid and were asymptomatic or even in the Spring when testing was so rare that had symptoms but never got tested. I assume it can’t hurt you, but since you were already exposed would it create a more severe reaction or is it not an issue? I haven’t heard one way or the other but I also haven‘t seen any plans to exclude people who had Covid so I assume it’s safe.
 

ToTBellHop

Well-Known Member
I probably have learned more about vaccines in the last 9 months than I ever wanted to;)

I am joking about getting both vaccines at once, but does anyone know what happens to someone who already had Covid? Can they get the vaccine still? Especially with the suspicion that a number of people had Covid and were asymptomatic or even in the Spring when testing was so rare that had symptoms but never got tested. I assume it can’t hurt you, but since you were already exposed would it create a more severe reaction or is it not an issue? I haven’t heard one way or the other but I also haven‘t seen any plans to exclude people who had Covid so I assume it’s safe.
There’s no risk in this case (or in the case of most vaccines—the vaccine acts like a booster). The vaccine isn’t at all similar to the virus. We make our own spike proteins. There’s also no intention of testing everyone for antibody levels (those tests are not terribly accurate, anyway). So it’ll be a moot point.
 

danlb_2000

Premium Member
New poll out shows 60% of Americans would get a vaccine if it was available today. This is up from 51% in Sept but down from 72% in May. Of the 40% who say they probably (21%) or definitely (18%) wouldn’t get the vaccine 46% say they would consider getting the vaccine after seeing others get it and more information is available. That adds 18% to the original 60% to get to a total of 78% of the population. With a vaccine that’s at least 90% effective that means 70%+ immune which should be good enough to reach herd immunity.

On distribution timing, the 60% ready to go now is just under 200M Americans so likely to take at least 4-6 months to vaccinate. By that time the other 40% will have plenty of data to go on. These numbers are likely to improve over time too as more people start to take the vaccine and there’s a public PR push to ensure people it’s safe and effective.


The wild card is how much misinformation takes hold. I already slapped down a post from a friend today claiming that the Pfizer vaccine causes sterility in woman.
 

GoofGoof

Premium Member
Original Poster
Most of the focus is on Pfizer and Moderna with the hearings and FDA approval expected this week and next and on the issues with the AstraZeneca trial in the UK, but here is a small update on the JnJ vaccine also in stage 3 trials rights now.
Johnson & Johnson said late Tuesday that health regulators in Europe and Canada had started a real-time review of its COVID-19 vaccine candidate after preliminary results showed that the shot triggered the production of antibodies and immune cells against the virus.
This is now the 4th vaccine candidate to apply for review in Canada (Pfizer, Moderna and AstraZeneca are the other 3). It is possible some specific US trial results could be available before the end of the year and the trial should reach the 2 month safety milestone some time in early January so if everything looks good it could have FDA EUA by the end of January. This is the vaccine that is testing both a single dose and 2 dose regiment in their trials and the single dose regiment looked promising in early trials. This one also does not need to be kept frozen.

 

danlb_2000

Premium Member
Pfizer vaccine shows a 52% efficacy after the first dose. This is pretty good considering there was a time when we thought the the total efficacy of a vaccine wouldn't be much better then this.

 

GoofGoof

Premium Member
Original Poster
In case anyone missed it, the committee voted 17-4 to recommend emergency use authorization of the Pfizer Covid vaccine for patients 16+. The 4 no votes were primarily concerned with 16 and 17 year olds being included in the EUA since the number of children in the trial was low and the risk for kids is not considered as serious.


One other piece of information that came out of this is that Pfizer plans to apply for full authorization by April or sooner and the FDA wants to keep the placebo group in tact (unvaccinated) until full approval.
 

Goofyernmost

Well-Known Member
In case anyone missed it, the committee voted 17-4 to recommend emergency use authorization of the Pfizer Covid vaccine for patients 16+. The 4 no votes were primarily concerned with 16 and 17 year olds being included in the EUA since the number of children in the trial was low and the risk for kids is not considered as serious.


One other piece of information that came out of this is that Pfizer plans to apply for full authorization by April or sooner and the FDA wants to keep the placebo group in tact (unvaccinated) until full approval.
Something about that seem wrong. They volunteered to be in the study to help the world out of this pandemic, but also to help themselves be somewhat protected and now because they volunteered they are going to be excluded from benefiting from the vaccine. Why not just sign up those that are against the vaccine and not planning to get it and study how they reacted to not having it. They made that decision anyway, they should have the courage of conviction strong enough to be helpful in perhaps proving themselves correct.
 

GoofGoof

Premium Member
Original Poster
Something about that seem wrong. They volunteered to be in the study to help the world out of this pandemic, but also to help themselves be somewhat protected and now because they volunteered they are going to be excluded from benefiting from the vaccine. Why not just sign up those that are against the vaccine and not planning to get it and study how they reacted to not having it. They made that decision anyway, they should have the courage of conviction strong enough to be helpful in perhaps proving themselves correct.
Pfizer said they wanted to vaccinate the placebo group as soon as the vaccine was approved. The FDA wants them to wait for full approval (probably March or April). One fear is that people will just leave the trial and get the vaccine anyway if they are eligible. There’s nothing to stop them. That’s actually a bigger concern for the other trials. JnJ and AstraZeneca aren’t done yet but the fear there is their trial participants will jump ship and get the Pfizer or Moderna vaccine when eligible rather than wait to find out if they got the vaccine or placebo and if the vaccine is as effective. If that happens they may be delayed in getting approval.

The other issue is tracking when the vaccine loses effectiveness. If the trial lasted 2 full years then you would be able to track the placebo and vaccinated groups together and know when the efficacy of the vaccine started to drop off. Obviously that won’t happen since they won’t ask people to wait 2 years and if they do most won‘t do it. If I were in the trial I wouldn’t wait 2 years if I got the placebo. They can still track the original vaccine group for 2 years but they won’t have a control group to compare to. Hopefully cases drop dramatically enough that it doesn’t matter.
 

Register on WDWMAGIC. This sidebar will go away, and you'll see fewer ads.

Back
Top Bottom