Disney Experience
Well-Known Member
A nice side by side comparison of the various types of vaccines:
The spikes are mounted on the virus body (‘the nucleocapsid protein’). But the thing is, our vaccine is only generating the spikes itself, and we’re not mounting them on any kind of virus body.
It turns out that, unmodified, freestanding Spike proteins collapse into a different structure. If injected as a vaccine, this would indeed cause our bodies to develop immunity.. but only against the collapsed spike protein.
And the real SARS-CoV-2 shows up with the spiky Spike. The vaccine would not work very well in that case.
So what to do? In 2017 it was described how putting a double Proline substitution in just the right place would make the SARS-CoV-1 and MERS S proteins take up their ‘pre-fusion’ configuration, even without being part of the whole virus. This works because Proline is a very rigid amino acid. It acts as a kind of splint, stabilising the protein in the state we need to show to the immune system.
Orange county FL
Registration and appointment for OC opens to 16+ tomorrow....
Orange county FL
Registration and appointment for OC opens to 16+ tomorrow....
This should allow a WDW vac site no?This will be for 8,000 appointments - Pfizer only.
These have gone fast before - if you are going to make an appointment, make sure to pre-register to save time!
Seems to be a trend, we need to do betterLooking at yesterday’s number, looks like the spring break spike has begun. Sigh.
Let hope it’s short lived. On the bright side we are adding to the number naturally “immune”. Immune is immune, but I’d rather have a sore arm and a potential headacheLooking at yesterday’s number, looks like the spring break spike has begun. Sigh.
If they do that they should have Mickey Mouse giving the shotsThis should allow a WDW vac site no?
What? They didn't use any of the mitigation measures AND were not vaccinated? How rude.Looking at yesterday’s number, looks like the spring break spike has begun. Sigh.
I would agree if the positivity rate were higher, but it's pretty much right where it's been on average for the past month.Looking at yesterday’s number, looks like the spring break spike has begun. Sigh.
Site examples of states who removed limitations and have had spikes recently? I'd point to places like PA and NJ, but they've been going up even before removing any limitations. Then there's the horror of Michigan.Limitations disappear and spikes happen. Are they related?
No, please no more surges. Is this getting even worse with variants. Pandemic will keep longer as expecting....Is the cases will go down by July as masks and social distancing will be removed soon for good.I can't wait to see all of the limitations rapidly go away as the numbers plummet in the next month or two. Right now it's still hard to plan travel even domestically given capacity limitations and ticket availability. Internationally countries are being hesitant to give even vaccinated people a pass.
Surges are not a good thing, but one thing to monitor is hospitalizations. As more are vaccinated, fewer cases should result in severity requiring hospitalization.No, please no more surges. Is this getting even worse with variants. Pandemic will keep longer as expecting....Is the cases will go down by July as masks and social distancing will be removed soon for good.
Register on WDWMAGIC. This sidebar will go away, and you'll see fewer ads.