I pack many of the things mentioned. We drive to Disney so I have a "Disney Bin" of stuff: collapsible bins in a few sizes (for holding keys, receipts, and other small items; for carrying numerous mugs to the food court to refill; to hold socks, undies, swim suits, etc. when we don't have enough drawer space.), various sizes of ziploc bags, garbage bags, travel-sized power strips, clothespins, magnetic bulldog clips, pop-up hampers, duct tape, Scotch tape, small paper tablet, post-it notes (for covering the auto-flush sensors when a child is terrified of being "flushed" on while still sitting on the toilet), scissors, sharpie, air freshener, Mini M & M container filled with pennies and quarters for the pressed penny machines (I also take a tube with just quarters and an envelope of dollar bills to use in vending machines in the hotels and rest stops for the drive down and back home), travel packs of Clorox wipes and anti-bacterial hand wipes, night lights, and a tennis ball (to roll under our feet after a long day of walking in the parks. Also helps to loosen up tightened hamstrings.). I also pack a small first aid/pharmaceutical bin but have cut back dramatically on that one. I take pack plenty of the meds we know we will need (adult pain relievers and allergy meds). But I only take a few doses of things we *might* need: stomach meds, children's fever reducer, etc. because I just don't want to be stuck needing it in the middle of the night -- if we need more I'll either get it in the gift shop or we'll drive off property for it. That first aid kit also includes Body Glide, Anti-chafing cream (that one gets used almost every trip), first-aid cream, Bio-Freeze, a heating pad, various sizes of band-aids, blister band-aids, and an ice pack. The first aid kit stays in the room but I put a few band-aids and the doses of any meds we need in the parks in my pocket before we leave the room.