www.timesofisrael.com
These Israeli studies,
Any idea why they don’t seem to line up with data elsewhere?
What does everyone here make of this?
I suspect it’s a combination of things. I know everyone is eager to reject it, but I think it told us things we should pay attention to. My not a doctor guesses...
A. Delta works fast. Faster than it takes for the T-cells to hop into action. So if your neutralizing antibodies aren’t in the fight and have waned over time, a large amount of virus replicates. Enough for people to test positive. Enough for people to be symptomatic.
However, if your T-cells still do their thing, and fight it off without you getting seriously ill... This is still fine, but the messaging about what you can expect now that you’re vaccinated will need to change.
Against severe illness the Israel studies still show high numbers. It’s against any infection that it’s an issue. And that number we aren’t even tracking. So of course we are blind to it.
B. People with immunodeficiencies, whether due to age or conditions probably need boosters to replenish their neutralizing antibodies because their bodies might not get those T-cells into action well enough to fight off more serious infection.
I think this is telling us things about the differences between reliance primarily of T-cell and B-cells vs still having the NAbs in your blood, and the speed and intensity of Delta.
I think we haven’t seen those numbers here because a bunch of people only got vaccinated in April or later, and still have higher levels of NAbs. And we are still a little early in Delta’s wave. However, I did start seeing that since a large percentage of care workers are unvaccinated some care homes are starting to see outbreaks in their facilities again. Of course, states have given up tracking those when everything improved. Anyway, give us time and I think we’ll start seeing some of the same things of infections in older people too.
This still means Delta is a son of a ... and you would rather have those T-cells, B-cells and NAbs via being vaccinated, even if they are a little slow vs not having them at all (unvaccinated).