Might want to read a bit more:
New coronavirus variant in NYC has vaccine-evading mutation
The variant, dubbed B.1.526, is on the rise in the city.
www.livescience.com
Experts say the impact of the new B.1.526 variant on transmissibility, disease severity, and risk of reinfection is not known. But the Columbia study shows the variant shares some concerning characteristics with the variants identified in South Africa and Brazil,
which may be less responsive to some treatments and vaccines.
Health experts are seeing red flags in coronavirus variants that were first discovered in Brazil, New York and California. Here's what they say.
www.usatoday.com
Scientists concerned over New York's 'escape variant'
Health officials are warning about a COVID-19 variant spreading in New York, saying the current vaccines may be less effective against the new strain as more Americans are getting the shots.
abc7ny.com
"particularly in the New York City metropolitan area. In addition to the E484K mutation, these variants also harbor a D235G substitution in spike that might help to
reduce the efficacy of neutralizing antibodies."
The E484K mutation in the spike protein of SARS CoV-2 contributes to immune escape from monoclonal antibodies as well as neutralizing antibodies in COVID-19 convalescent plasma. It appears in two variants of concern – B.1.351 and P.1 - but has evolved multiple times in different SARS-CoV-2...
www.medrxiv.org
Yes -- It is quite different, and quite a reason for concern. It is hoped and expected vaccines will remain effective, though they are expected to be less effective, may require boosters, etc.