Been hearing about remsdesivir and chloroquine for a few weeks now from China and other places.For anyone looking for some potential goods news to hope for here’s a clip from an article talking about some potential treatments for the virus that could be available as early as next month. A true vaccine may still be a year away, but if some drugs which already went through some or all stages of the approval process can be effective at lessening the symptoms and/or preventing the spread that may be the stop gap that gets us to a real vaccine. Here’s the relevant section from a longer article:
On the bright side, both Haseltine and Klausner said there’s reason to believe therapeutic treatments may be available to the American public within just a few months.
When SARS and MERS came along, Haseltine explained, “there was a huge effort to create drugs,” many of which were promising leads. But then those two outbreaks, which both had significantly higher fatality rates than the novel coronavirus, petered out. Amid the new pandemic, physicians have picked back up on those prospects and begun to test them more aggressively.
Haseltine said the likelihood is that at least one treatment option will be available through the public-health system within weeks or months, and might even prevent the virus.
Klausner named two specific antiviral agents that look promising, including remdesivir and actemra, the latter of which he called “essentially a synthetic antibody” that is “currently being used and recommended for use in China” to treat the new coronavirus. It has been jointly manufactured by Roche and Chugai Pharmaceutical for use as an anti-inflammatory drug for rheumatoid arthritis.
Meanwhile, remdesivir, which was created by Gilead Sciences, has been reportedas the most promising possible treatment for the virus because it is a “broad spectrum” drug that has shown effectiveness against various viral targets in lab testing.
Officials expect outcome data on remdesivir as early as April, and there have been promising studies in cell culture and animal models, according to Klausner. “People are using the drug now in the United States under compassionate use,” he said, referring to an agreement between the manufacturer and the Food and Drug Administration that makes it available for some high-risk infected individuals. “It’s being used internationally as well.”
“Once the data are available and presented to the FDA, I would expect that FDA approval would be within a few days to a couple of weeks,” followed by a public rollout, said Klausner, who explained that there are multiple ways to use antiviral drugs, including prevention and treatment.
Unfortunately, until this is approved, as you stated, a hospital needs to reach out to Gilead to get compassionate use approved for an individual patient to use remsdesivir. Only a few hundred patients around country have received it so far. I'm sure this will change quickly. It would be nice if it was sent to every single hospital for future use.
Australia is trialing these in 50 hospitals soon and also looking at using 2 different drugs together as a cocktail.