I would say "Very useful additional tool in the arsenal", but not quite a game-changer yet. Vaccines and the monoclonal antibody infusions already do most of the work of this medication. The biggest difference is that an oral medication is much more scalable than an infusion. And in general, people usually show far less resistance to taking pills than an injection. I've found that in at least some people, all the resistance phrased as "I'm not putting that in my body!" is really just a mental construct to justify a simple fear of needles.