I feel this!! We had to cancel Hawaii last May for the obvious. Had to cancel WDW over Labor Day and move a planned December to January, as our daughter couldn't get off work. I had to have back surgery in November and we were thinking January could still work. Nope! Had to have another surgery in December so January is out
I have it tentative for May, but you're correct that airline is locked in. And flight prices have doubled with the vaccine. It's quite deflating.
Smart move with waiting on flights. And hopefully you'll get your glimmer of hope soon!