This is slightly different, but my DH struggles with anxiety and takes medication to fly. He took a little too much of it on our flight down and his brain, body, and subsequently his mind were extremely effected by this misstep for the entire week of our trip. He was also anxious and stressed due to us buying a house in the middle of all this and recent work travel he accompanied me on two weeks prior.
We had to cancel many ADRs, I counseled and coached him the whole time, took things super slow if we even went to a park, and to be honest while he napped in the middle of the day in our room I just cried on the balcony for a while. I did was so emotional selfishly because I wanted he and I to enjoy ourselves and be carefree, in release of the stress of the house, and of course mostly for him that he was struggling so much and was not enjoying a vacation he really needed and deserved. Instead, he was beyond miserable.
He ended up pushing himself to leave the room and got a hair better, but truthfully I survived the trip by creating my own happiness and enjoyment in my own head as I couldn't really share it with him like on rides, singing along to happy songs, and through little experiences like being really present while taking in my favorite sites or smiling my face off in the dark on my favorite rides. I made the choice to enjoy myself.
It was hard but if it's the worst thing we encounter, we are pretty lucky people. But yikes I hope it never happens again. I'd rather have a cold the whole time.