However, I believe Disney will look carefully at what's happening in the country and will adjust accordingly. If enough people get vaccinated that case numbers are low enough for society as a whole to be doing away with masks in most situations, Disney will do away with them too. I think Disney really hopes to be rid of masks in time for the 50th anniversary.
Now that the Biden administration confirmed that we will have enough vaccine for all adults by mid-May that pretty much confirms that vaccines will be open for the general public by April so the timeline could/should be accelerated. Does that mean relaxing of restrictions sometime this Summer? Its a decent possibility. I think it’s a safer bet that things will be pretty relaxed by the 50th on 10/1.
Disney will adhere to whatever CDC guidelines are in place on that date, no matter what fans' or executives' hopes may be.
It's far more important for their business that they make guests feel safe, than do away with masks, even if only slightly prematurely, for any reason. Considering their actions up to this point in the pandemic, I wouldn't expect Disney to risk any sort of blowback by getting ahead of the CDC in terms of lifting restrictions.
And while there is plenty of reason to be optimistic at the moment, keep in mind that having enough vaccines for all adults by mid-May is very different than having administered vaccines for those adults.