I recommend JetBlue -- especially if you're an anxious flyer, as the seatback TVs are a wonderful distraction! I also like to take a deep breath, say a little prayer before takeoff, and remind myself that the odds of a plane crash are something like 1 in 31 million -- and that the only realistically dangerous part of the journey was the part I've already completed -- the car trip to the airport!
We save about 50% on our JetBlue flights by using a JetBlue American Express card. (There is a $40 annual fee. I use it for practically everything and pay it off in full every month, on time, so there's never any interest charges or late fees.) Every year, putting about $2,500 per month on the card, I earn enough points for one roundtrip flight between Syracuse, NY and Orlando.
With JetBlue, cheapest fares are released first and the price only goes up. You can sign up on their website for e-mail notifications every time the schedule is extended and new fares released. In the event you book and there's a special discount or sale offered later, you can have the difference refunded as a credit toward future travel.