Assuming you don't have daytime admission, you're only going for one night, and won't buy Express Passes, yes, it's invaluable.
While long lines will be inevitable, the first 90 minutes of the event are critical to stay ahead of the crowds and knock out 3 or 4 houses. It's also worth having a general gameplan. The first and last 90 minutes of the night will see your shortest lines. In between, you can enjoy the scare zones, the show (arrive at least 30 minutes early), food and drink booths, a ride or two, and any houses you decide are worth the wait or that happen to get short lines. (Just don't cross the entire park trying to chase a short line that shows up in the app wait timed, others will be doing the same and flood the line before you get there. I speak from personal experience)
Orlando Informer often comes out with a touring plan for the houses. I'll look and see if I can find a link to this year's.
Edit:
https://orlandoinformer.com/universal/halloween-horror-nights/
-Rob