Used to drive all the time from Vermont to Disney. We didn't rush it. We would leave home on Saturday Morning, drive to Fredricksburg, VA., spend the night. The next day would be shorter we only went as far as Walterboro, SC and the next morning head out to Orlando. We arrived at our hotel usually around 2 PM. Picked up supplies, sat by the pool and planned our next day in WDW after we had rested up.
Reverse procedure on the way back with different stops but the same basic time on the road per day. When I told people what we did, they just can't believe that we didn't just keep driving. Well, it was what worked for us and I have never regretted doing it that way.
After my divorce, I kind of mixed it up. Sometimes I'd take a road trip, sometimes I'd fly and equally enjoyed either one.
Now living in NC, I jump in the car and drive straight through to Disney.