My personal opinion would be no. I have taken this particular tour 4 times and once we had someone in a motorized cart. The first thing the CM asked was if they could walk. There is alot of stairs, walking, passageways, obsticles that you have to walk over, you are constantly in and out of the vans. It is totally backstage and a semi off-road experience. I would think Disney could accomodate the person, but I think it may be difficult if they are 100% wheel chair bound. The best thing to do is to contact Disney's tour department and ask these specific questions with them. This is only my opinion, but sorry - no I don't think it is a suitable tour.