Living with Patrick Stewart
In my opinion, the Altamonte area has served as a good place to live. There are a number of schools in the area. It is well developed and within 20 minutes of Downtown Orlando (if traffic is moving at a good pace.) It is about 45 minutes from Disneyworld, which is a good distance to avoid those heavy tourism areas, yet close enough to drive to every 2 weeks. It's about 30 minutes from Universal Orlando. Longwood/Apopka are also nice areas, so long as they are the areas nearest Altamonte. Maitland is also near the Altamonte area and has its nice areas. A lot of people see the quickly evolving Oveido area as a nice location, however, traffic in this area can get pretty nasty due to the adjacent University of Central Florida (UCF), which if it grows at its current rate will soon be bigger than the University of Florida (UF), becoming the biggest university in Florida. The Oveido area is also a good driving distance from most professional jobs, depending on where you will be working.
I can only speak for the areas that I am familiar with, and I am pretty familiar with these areas. The best thing to do might be the same thing that you did for college, and travel down here taking a week to explore the areas. Although it may be more expensive, you'll probably want to live within 10 minutes of Interstate-4. That's the main "bloodline" here in Orlando. Any further than that an commuting will seem more of a hassle every day. I-4 runs from Daytona Beach (east) to Tampa (west), hitting Disneyworld in between. Lake Mary, Altamonte, Maitland, are all adjacent to I-4, and some areas of Longwood and Apopka are within a 10 minute drive.
Hope this helps,
Tk