My tip is - [if he has never used a scooter, or doesn't use one very often] try to get some practice before you go. Other guests are often not paying attention to scooters and don't yield to them as they should, so the rider/driver has to be ready for "safety avoidance maneuvers". Places like grocery stores, Sam's, Costco, BJ's, etc are good places to practice, that provide scooters (in case he doesn't have his own & will be renting one while there).
Also, just fyi, guests on scooters who use Disney's bus transportation, will need to be able to drive it onto the bus and back it into the parking spot on the bus.
Cast Members will be glad to help with directions to Access areas to board an attraction (if he isn't able to stand in a line, whether standby or FP).
Just thought of another one - he will probably need to plug it in every night to re-charge the battery, and could need to plug-in during a mid-day break (if you take one), especially if you plan to be out from early until late - just be aware of how much charge he has remaining if you have been out for most of the day. I have seen guests drive right into their rooms for the night, I assume it's for security & for re-charging. Sorry if this is all "old news" or common sense that didn't need to be said, but having never needed to use one, I'm not sure I would have thought of some of these if I hadn't needed to be aware of info for others.
I hope you have a Wonderful, Magical time!!!