If it's limited to 100 pins, most likely, it will sell out within minutes. That's a tiny amount. Most limited editions have more like 1,500 or so.
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edit: I just noticed you said "framed" set. That's a different story. If it's one of the framed sets that are a few hundred dollars, no, it won't sell out as quickly as just pin release in general. I guess it depends on how hot this one turns out to be. I know they often don't fully sell out of the framed sets during MNSSHP or MVMCP, but I think those are larger edition than 100. So, it's a toss-up with a framed set. If it's super sought-after, sure, it might sell out right away. If not, it won't.