Lake Nona was a giant loss, both for Disney and Orlando. Disney should have persevered, but bowed to internal pressure (more than external) and left what would have been a revolutionary project for them in the long term. Moving to Orlando would have significantly improved WDI. I'm much more disappointed that many in the old guard took what should have been an issue about uprooting livelihoods and lifetimes, and made it political. Partly because none of those same people have spoken out against DLAD (or taken their cheques from Miral), despite similar (or even worse) issues.
But I'm most upset because it would have been a massive home run for Orlando, which has suffered massively since TAIT effectively vacuumed up the major 3rd party design studios, laid off tons, and distributed much of the work that formerly went through their Orlando offices elsewhere (particularly PA, but also various other locations). It would have been Creative's equivalent on steroids, and a major boost to a relatively stagnant economy in Lake Nona (outside healthcare and a few other things). UCF loved the idea (proposals existed to feed grads from Rosen, the themed experience programs, and their engineering school, among others, into Imagineering in an expanded partnership that would have displaced SCAD and certain UC schools as Disney's major partner and feeder University), and it had near universal (pun unintended) support from the community. Think of all the associated jobs that would have been needed to support all the people who moved here, and the long-term development that would have spread as a result - no wonder why both Orlando and the County begged Disney to do this even despite turmoil. The biggest loss for Central Florida economically since the Navy moved out, and it's not even close.
Did it impact future Imagineers? Almost certainly, but I think the issue is much more broad. Management is clearly not up to the task of being a transistion from what was clearly a generation of some of the best in their craft to ever live. A lack of mentorship is one issue, but a lack of support, resources, or even planning (much less good ideas) are all other issues. Firing the best, and replacing them with lesser experience (and cheaper) options will bite Disney in the bum soon (if it hasn't already with Tiana and other underdelivered and underdeveloped projects). That's something I heard as far back as 2019 from various former Disney figures, and even more so during and after the pandemic. It's taken years to roost, we're only seeing the after-effects now and will for decades if nothing changes.